Methods: This is a retrospective series of acute aspirin overdose from two. We investigate our experience of aspirin overdose and the effectiveness of charcoal and bicarbonate administration over 20 years. likely to occur in smokers and occurs later in treatment. Management is guided by research reported over 50 years ago when chronic aspirin toxicity was common and accounted for significant morbidity. restlessness, trouble standing still Tardive dyskinesi EPS. facial grimacing, involuntary upward eye movements, muscle spasms of tongue, face, neck, and back Akathisia EPS. hemodialysis may be necessary barbiturate toxicity nystagmus, ataxia, respiratory depression, coma, pinpoint pupils, hypotension and death. Severe: extreme polyuria, tinnitus, involuntary movements, blurred vision, seizure, severe hypotension leading to coma and possible death from respiratory complications neuroleptic malignant syndrome sudden high fever, bp flucuations, dysrhythmias, muscle rigidity, diaphoresis, drooling and altered mental status Neuroleptic malignant treatment diazepam for anxiety, dantrolene and bromocriptine to induce muscle relaxation lithium toxicity treatment emetic, gastric lavage or urea, mannitol or aminophylline to increase rate of excretion. Dysrhythmias and seizures at higher levels digoxin toxicity yellow halo in eyes, visual disturbances, bradycardia, nausea, vomiting digoxin antedote digoxin immune fab (digiband) atropine for bradycardia lithium toxicity diarrhea, nausea, vomiting, polyuria, muscle weakness, tremors, lethargy: Therefore, antidote means to give against. You can break up the word to remember the definition. Warafarin overdose antedote vitamin K heparin/ enoxaparin overdose antedote protamine theophylline toxicity mild: GI distress and restlessness. An antidote is a remedy or medication given to counteract the effects of poison, toxicity, or overdose.
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